暖宫种子汤治疗多囊卵巢综合征疗效观察

Clinical study on treatment of polycystic ovary syndrome with nuangongzhongzi recipe

目的观察暖宫种子汤对多囊卵巢综合征(polycystic ovarian syndrome,PCOS)促排卵的临床疗效。方法收集符合PCOS纳入标准的患者90例,随机分为暖宫种子汤(A组)、克罗米芬组(B组)和联合用药组(C组)各30例。记录卵泡发育、子宫内膜生长、宫颈黏液性状、基础和促排卵治疗后性激素、胰岛素等指标。结果A组和C组的子宫内膜厚度和宫颈黏液评分优于B组,注射HCG日B组和C组的卵泡直径大于A组,差异有显著性(P<0.05)。各组排卵率分别为59.26%、66.67%和73.33%,差异均无显著性(P>0.05)。结论暖宫种子汤能有效诱导PCOS患者排卵,与克罗米芬合用能改善对子宫内膜和宫颈黏液的不利影响。

Objective To study the effect of Nuangongzhongzi Recipe on polycystic ovary syndrome （PCOS）. Methods Ninety PCOS patients were randomly divided into 3 groups： Nuangongzhongzi recipe group（ group A ,30 cases treated with Chinese traditional medicine） , the clomiphene citrate group （group B ,30 cases, treated with clomiphene citrate） and group C（ 30 cases, treated with clomiphene citrate and Chinese traditional medicine）. The follicle figures and endometrial diameter were recorded, and the sex hormone and insulin level were determined before and after treatment.Results The ovulation rate of these three groups was 59. 26% ,66. 67% and 73.33% respectively. No significant differ- ence of ovulation rate was found between the three groups. The endometrial diameter and cervical Insler＇s scores were significantly higher in group A and group C than that in group B. Conclusion The Chinese traditional medicine- Nuangongzhongzi recipe can raise ovulation rate, and significantly reduce the side effects of clomiphene citrate in PCOS patients.