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3-叔丁氧甲酰基氨基吡咯烷催化酮和硝基芳基乙烯的不对称Michael加成 被引量：2

Micheal Addition of Ketones to Nitro-aryl-ethene Catalyzed by 3-Butoxycarbonylamido-pyrrolidine
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摘要 用3-叔丁氧甲酰基氨基吡咯烷催化酮和硝基芳基乙烯的不对称M ichael加成,并考察了反应物结构对加成的影响,得到了较高的收率和较好非对映选择性。 Asymmetric Micheal addition reaction of cyclohexanone and pentan-3-one to nitro-aryl-ethenes was studied using 3-butoxyearbonylamido-pyrrolidine as a catalyst. The influence of reactant structure on the addition reaction was investigated. The addition poduets were obtained in high yields and diastereoselectivities.
作者 李坤 李建国 袁伟成 张晓梅
机构地区 中国科学院成都有机化学研究所 中国科学院研究生院 河南师范大学化学与环境科学学院
出处 《合成化学》 CAS CSCD 北大核心 2009年第2期239-242,259,共5页 Chinese Journal of Synthetic Chemistry
基金 四川省青年科技基金资助项目
关键词 吡咯烷 硝基芳基乙烯 酮 不对称MICHAEL加成 pyrrolidine ketone nitro-aryl-ethene asymmetric Micheal addition
分类号 O623.54 [理学—有机化学] O625.61 [理学—有机化学]
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参考文献10

  • 1Xu Y M, Zou W B, Sunden H, et al. Small peptidecatalyzed enantioselective addition of ketones to nitroolefins [ J ]. Adv Synth Catal,2006 ,348 :418 - 424.
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合成化学
2009年 第2期

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