CD62p与早期诊断肺血栓栓塞症

CD62p and Early Diagnosis of Pulmonary Thromboembolism

目的探讨检测CD62p在早期诊断PTE患者中的临床意义。方法采用流式细胞术分别测定正常人群组、高危组、肺血栓栓塞症组人群的CD62p,比较3组人群中CD62p的区别。结果PTE患者CD62p高于高危人群及正常对照组(P<0.01);高危人群组CD62p高于正常对照组(P<0.05)。结论PTE发生后CD62p水平升高,与高危人群比较有显著性差异,高危组与对照组比较有显著性差异。因此,CD62p可作为早期诊断肺栓塞的有效指标。

Objective To investigate the clinical implication of CD62p to the diagnoses of PTE at initial stage.Methods Apply ELISAto measure the level of CD62p of the non-PTE group,high PTE-risk group and PTE patient group respectively,compare CD62pvolume among the three groups.Results The PTE group＇s CD62p volume exceeds that of high PTE-risk group and non-PTE group（P〈0.01）,the high PTE-risk group＇ s CD62p volume exceeds that of non-PTE group（P〈0.05）.Conclusion When PTE occurred,the CD62p volume increased,significantly distinguished from high PTE-risk group,and the CD62p volume of high PET-risk groupalso significantly higher compared to non-PTE group.Consequently,CD62p is a effective indicator for initial stage PTE diagnosis.