糖心通对糖尿病性心脏病的保护性机制临床研究

Clinical Study on the Protective Mechanisms of Diabetes Heart Disease by Tangxintong

目的:观察糖心通对糖尿病性心脏病的保护作用,并对其机制进行临床研究。方法:将120例糖尿病性心脏病患者随机分为治疗组和对照组。其中治疗组用糖心通合剂治疗观察60例,对照组用糖脉康治疗观察60例。治疗8周后观察患者的症状、体征并检测心肌供血、血糖、HbAlc、胰岛素水平、血浆高同型半胱氨酸(HcyM)、脂联素(APN)等指标。结果:临床观察发现,糖心通不但可有效的改善糖尿病性心脏病患者的症状、体征,改善患者心肌供血,而且可显著降低血糖、HbAlc和胰岛素水平,明显改善血浆高同型半胱氨酸(HcyM) 、脂联素(APN),与治疗前比有显著性差异,且明显优于对照组。结论:糖心通对糖尿病性心脏病有显著的防治作用,值得进一步推广和研究。

Objective： To observation the protective function of Tangxintong to diabetes heart disease,and conducts the clinical research to its mechanism.Methods： Considering the basis of above,we organize Tangxintong.And then we take the Clinical Research.Clinical research：120 cases of Diabetic Cardiopathy were randomly divided into treatment and control groups.The treatment group with 60 cases was given Tangxintong and the control group wih 60 cases was given Tangmaikang.After 8 weeks,the experiment index were compared to those in begining.Results： The clinical observation discovery,the sugar regards clear not only may the effective improvement diabetes patient＇s symptom,the body draft,improves the function of the heart,moreover may remarkably reduce the blood sugar and HbA1c,obviously im-proves the blood to change,especially to patient＇s level of blood adiponectin、hyperhomocysteinemia、IL-18 has the remarka-ble improvement,compared to has significance the difference with the treatment before,also obviously surpasses thecomparison group.Conclusion：The Tangxintong has the remarkable prevention function to the diabetes heart disease.It is worth further promoting and studying.