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粒细胞集落刺激因子与心血管疾病关系的研究进展

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摘要 心血管疾病已成为我国的常见病及多发病，其发病率有不断上升的趋势。心血管疾病的相关研究显示心肌不是终末分化组织，在心肌损伤后可以进行一定程度的有丝分裂［1］，但单纯依靠其自身有丝分裂难以修复受损的心肌，只能由成纤维细胞填充，最终为瘢痕组织替代，并逐步发生心室重构，形成慢性心力衰竭。现有的内外科治疗都不能解决心肌细胞损伤修复的问题，目前有研究表明动员干细胞可以治疗心肌损伤。因为自体同源性及来源充足易于获取，使自体骨髓干细胞（bone marrow stem cells，BMSC）成为最佳种子细胞。粒细胞集落刺激因子（granulocyte colony stimulating factor，G-CSF）是骨髓干细胞强有力的动员剂，
作者 王娓娓 赵雅静 张红苗
机构地区 昆明医学院第二附属医院
出处 《中国医药导刊》 2009年第1期49-51,共3页 Chinese Journal of Medicinal Guide
关键词 粒细胞集落刺激因子 骨髓干细胞 心血管疾病 进展
分类号 R54 [医药卫生—心血管疾病]
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参考文献20

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二级参考文献28

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中国医药导刊
2009年 第1期

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