梨小食心虫性信息素微囊化及释放特性

Microcapsulating and Controlled Release Characteristics of Sex Pheromone of Grapholitha molesta

以乙基纤维素为囊壳,采用相分离法制备了梨小食心虫性信息素微囊粒剂;同时研究了乳化剂、控释剂、搅拌速度、有机相中溶剂加入量及水相中聚乙烯醇浓度、有机相滴加速度等因素对该微囊粒剂的平均粒径及包覆率的影响,并进行了室内释放分析。结果表明,使用乳化剂700#较为理想;以油酸甲酯、邻苯二甲酸二丁酯或正十二烷为控释剂,均能制得包覆率较高的微囊粒剂;搅拌速度、有机相中溶剂加入量及水相中聚乙烯醇浓度、有机相滴加速度对微囊粒剂的平均粒径及包覆率的影响较明显。控制释放研究结果表明,在室内较稳定的条件下,能持续释放110d以上。

The encapsulated granule of the sex pheromone of Grapholitha molesta Busck was prepared by phase separating,using ethyl cellulose as shell material.The factors which affect the average diameter and encapsulating rate of encapsulated granule of sex pheromones of G.molesta,such as the varieties and quantities of emulsifier,the varieties and quantities of release controlling agent,the stir speeds,the content of organic phase,concentrate of PVA（polyvinyl alcohol） in water phase and the dropping speeds of organic phase,were studied.The results showed that encapsulated granule of sex pheromone of G.molesta can be prepared with high encapsulating rate using emulsifier 700^# as emulsifier and methyl oleate,di-n-butylphthalate or n-dodecane as release controlling agent;the effects of stir speeds,the content of organic phase,concentrate of PVA in water phase and the dropping speed of organic phase are obvious on the average diameter and encapsulating rate of encapsulated granule.The results showed that the encapsulated granules of sex pheromone of G.molesta have a sustained-releasing time of more than 110 days indoor.