儿童功能性消化不良与幽门螺杆菌感染的关系

The relationship between the helic0bacterium pyloric infection and the functional dyspepsia in children

目的探讨儿童功能性消化不良与幽门螺杆菌（HP）感染的关系。方法用ELISA法和胃液尿素酶试验检测163例功能性消化不良和54例健康儿童的HP感染情况。结果血清HP-IgG阳性申功能性消化不良组高于对照组（43．6％:14.8％，X2＝14．7，ｐ＜0.01），尿素酶试验阳性率功能性消化不良组也高于对照组（15．3％:3．7％，x2＝5．07，p＜o．05）。内镜检查15例患儿中，慢性胃炎12例（占80％）。经抗HP治疗功能性消化不良症状消失。结论儿童功能性消化不良与HP感染相关，HP是该疾病的主要病因之一。

Objective To search for the relationship between the helicobacterium (HP)pyloric infection and the functional dyspepsia in children. Methods Case-control research. There were 163 cases of functional dyspepsia and 54 normal children in control group. The serum HP-IgG was determined by ELISA. The gastric urea test was uscd. Results The rate of the serum HP-IgG was 43. 6 % in the functional dyspepsia and 14. 8% in normal children（X2＝l4. 7, P ＜0. 01 ). It was observed that the positive rate of the functional dyspepsia was higher than that of the control gruP (15. 3 %: 3. 7 %,x2＝5. 07,P〈0. 05). Among l5cases 0f the functional dyspepsia examined with the endoscope, l2cases suffered fr0m chronic gastritis.The symptoms disappeared after antibiotics were used. Conclusion The functional dyspepsia is associated with infec-tion of HP, which is an mainly etiological factor of the functionaldyspepsia in children.