摘要
通过建立四动脉夹闭所致大鼠急性全脑缺血再灌注模型，以脑含水量、局部脑组织血流量、血清和脑组织中一氧化氮含量为观察指标，初步研究了脑络通对缺血性脑损伤保护作用的机理。结果表明：脑络通对缺性脑损伤具有明显的保护作用。
To study the protective effect of Naoluotong(NLT) on cerebral ischemia,the acute whole cerebroischemiareperfusion rat model established by 4 occlusion vessels was used.The content of the cerebral tissue water,the regional cerebral blood flow(rCBF)and the nitric oxide(NO)content of brain and serum were observed.The results suggested that NLT can protect brain from ischemic damage by activating LargNO pathway.
出处
《安徽中医学院学报》
CAS
1998年第3期41-44,共4页
Journal of Anhui Traditional Chinese Medical College
基金
安徽省教委自然科学基金
关键词
脑缺血
药物疗法
脑络通
血流量
一氧化氮
Naoluotong(NLT)
Brain edema
Nitric oxide(NO)
NGnitrioLarginine
Cerebroischemia damage
Regional cerebral blood flow(rCBF)
