卡马西平联合甲钴胺对脑卒中后中枢性疼痛的治疗作用

The therapeutic effects of Carbamazapine combined Mecobalamine on central post-stroke pain

目的:观察和评价卡马西平联合甲钴胺治疗脑卒中后中枢性疼痛的治疗效果。方法:以卡马西平为对照,治疗过程中疼痛程度用视觉模拟评分法动态观察评价卡马西平联合甲钴胺对脑卒中后中枢性疼痛的疗效,并对疗效相关因素进行分析。结果:联合用药组较单药治疗组起效快,卡马西平用量少,不良反应发生率低。结论:联合用药治疗脑卒中后中枢性疼痛是一种非常有效的方法,值得进一步推广。

Objective： To observe and assess the clinical effects of Carbamazapine combined Mecobalamine on central post-stroke pain（CPSP）. Methods： The patients with CPSP were randomly divided into Carbamazapine combined Mecobalamine group and Carbamazapine group. Pain intensity was assessed with visual analague scale（VAS）. Other factors associated with symptoms were also investigated. Results： Combined group was more quickly in clinical effect, the dosage of Carbamazapine was low and the adverse effect was little. Conclusion： The combination therapy is an effective method, it is valuable to spread more.