摘要
目的:观察诺迪康胶囊治疗慢性疲劳综合征的临床疗效,并探讨其作用机制。方法:将108例慢性疲劳综合征患者随机分成诺迪康治疗组和归脾丸对照组,分别口服上述两种药物,28d为1疗程,观察治疗前后T淋巴细胞亚群中CD3+、CD4+、CD8+的数值、CD4+/CD8+的比值及免疫球蛋白IgA、IgG、IgM的数值变化。结果:治疗组总有效率为92.72%,对照组总有效率为75.47%,治疗组疗效优于对照组,差别有统计学意义(P<0.05)。治疗组治疗后CD4+、IgA及CD4+/CD8+的比值均降低;CD3+、CD8+、IgG、IgM的数值升高,且治疗组在升高CD3+、CD8+及IgG、IgM方面优于对照组(P<0.05)。结论:诺迪康胶囊治疗慢性疲劳综合征心脾两虚证具有较好临床效果,提高患者免疫功能是其重要作用机制之一。
Objective : to observe the clinical effect of Luodikang capsule to treat chronic fatigue syndrome and discuss the mechanism of action. Method: 108 cases of chronic fatigue syndrome were randomly divided treatment and control. The treatment was treated in Luodikang capsule and the control in Gui Pi pills. The course of treatment was 28 days. The numerical value of CD3^+ , CD4^+ , CD8^+ and CD4^+/CD8^+ , IgA, IgG and IgM were observed before and after treatment. Results : the total effective rate was 92.72% in the treatment and 75.47% in the control( P 〈 0.05 ). The value of CD4^+, IgA and CD4^+/CD8^+ were cut down and the CD3^+, CD8^+, IgG and IgM were rised after treating in the treatment group. Conclusion: Luodikang capsule has the function to treat Chronic fatigue syndrome( cardiosplenie asthenia). Its mechanism of action is maybe raise patient's immune function.
出处
《河南中医学院学报》
2009年第2期38-39,共2页
Journal of Henan University of Chinese Medicine
基金
河南省教育厅高校青年骨干教师资助计划项目(编号:262)
关键词
慢性疲劳综合征
诺迪康胶囊
免疫功能
Chronic fatigue syndrome
Luodikang capsule
immune functionodod