子宫颈电环切除术治疗宫颈上皮内瘤变的疗效研究

Loop electrosurgical excision procedure in treating 68 patients with cervical intraepithelial neoplasia

目的:探讨宫颈电环切除术(LEEP)手术方法和有关术后并发症的关系及其防治措施,手术后标本的观察处理原则。方法:采用LEEP对68例宫颈上皮内瘤变(CIN)患者进行治疗,对其疗效作回顾性分析。结果:术前术后病理诊断一致占39.71%(27/68);术后病理诊断级别下降占54.41%(37/68);术后病理诊断级别上升占5.88%(4/68)。宫颈管受累占5.88%(4/68)。术中出血达10ml仅1例。术后子宫颈管狭窄1例,术后盆腔痛2例。治愈率为95.59%,宫颈CIN残留1例,第一年内复查发现CINII持续1例,术后妊娠6例次。结论:LEEP是治疗CIN的安全有效方法,只要掌握手术指征,规范手术步骤,注意术后病理观察,可获得满意疗效。

Objective：To study the application of loop electrosurgical excision procedure（LEEP）, its complications and the prevention measures. Methods： 68 cases with cervical intraepithelial neoplasia（CIN） treated by LEEP were analyzed retrospectively. Results： The preoperative diagnosis of 27 cases（39.71% ）were in accordance with the postoperative ones. The postoperative diagnosis were downgraded in 37 cases （54.41% ）, and upgraded in 4 cases（5.88% ）. Intraoperative bleeding amotmted to 10 millilitres in I case. The cure rate was 95. 59%. 1 case with CIN II was found with persistence nature in 1 year. Postoperative pregnancy in all patients occurred 6 times. Conclusions： LEEP is a safe and effective procedure in treating CIN. Satisfactory results can be achieved by mastering surgical indications and standard procedures and paying attention to postoperative pathology.