2型糖尿病患者血液流变学和血糖的相关性分析

The correlation analysis of hemorheology and blood glucose of patients with type 2 diabetes mellitus

目的探讨2型糖尿病患者血液流变学的改变及与血糖的相关性。方法对58例2型糖尿病患者与64例健康对照者进行血液流变学检测,并通过t检验对糖尿病患者血糖与血液流变学指标的相关性进行分析。结果2型糖尿病组血液流变学指标与健康对照组差异有统计学意义(P<0.01),糖尿病患者除红细胞变形指数与血糖呈负相关外,其余血液流变指标均与血糖呈正相关。结论2型糖尿病患者血液流变学异常增高,导致微循环障碍是诱发多脏器功能受累的主要原因。

Objective To analyze the correlation between the change of the hemorhelogical indices and blood glucose in patients with type 2 diabetes mellitus. Methods The hemorhelogical change was detected in 58 patients with type 2 diabetes mellitus （T2DM group） and 64 healthy controls （healthy control group）. The test results were analysed via t teat. The correlation analysis was performed between hemorhetogical change and blood glucose results in T2DM group. Results There was statistical difference in hemorhelogieal change between T2DM group and healthy control group （P〈0.01）. In T2DM group, most of the hemorhelogical indices were positively correlative to blood glucose except RBC deformation index. Conclusion The microcirculation disturbance caused by significantly elevated hemorhelogical indices, is the main cause for multi-organ disfunction.