某高校2008级新生乙肝病毒感染情况分析

Hepatitis B Virus Infection Status of Grade 2008 Freshmen of Hunan University of Technology

目的了解我校2008级5459名新生乙型肝炎病毒感染情况,为乙肝疫苗的预防接种提供资料,为学校控制乙肝传播提供科学依据。方法应用酶联免疫法(ELISA)检测HBsAg,HBsAg阳性者进一步检测乙肝五项。结果HBsAg总体阳性率7.58%,低于全国一般人群的平均水平,从性别看,男生HBsAg阳性率为9.83%,女生为4.61%,两者比较有统计学意义;以城乡来看,城镇学生HBsAg阳性率为5.84%,农村学生为9.28%,两者比较有统计学意义;且以"大三阳"和"小三阳"两种感染类型为主。结论高校应做好新生入学时乙肝的防治工作,进行乙肝防治知识的健康教育,提高大学生对肝炎的认识及自我保护意识。对有传染性可能的学生应加强管理,对易感人群进行乙肝疫苗接种,防止乙肝在学校中传播。

Objective To survey the infection situation of hepatitis B virus among 5,459 freshmen of Hunan University of Technology, and to provide scientific evidence for vaccination and prevention of the spread of the disease in the college. Methods HBsAg was tested using ELESA method, and freshmen with HBsAg positive were further detected the five serological markers of hepatitis B. Results The total positive rate of HBsAg was 7.58 %, which was lower than the average percentage of the whole country. The difference of HBsAg between males （9.83 % ） and females （4.61% ）, students from city （.5.48 % ） and rural areas（9.28 % ） was significant. There were two types of infection, including ＂HBsAg, HBeAg, and HBcAb＂ and ＂HBsAg, HBeAb, and HBcAb＂. Conclusions The college must take some precaution measures for prevention of Hepatitis B among freshmen; developing health education about hepatitis B- related knowledge and improving the consciousness of self- protection are also important. It is necessary to strengthen management of students with hepatitis B, inoculate hepatitis B vaccine for susceptible population, and prevent the spread of the disease in the college.