长托宁治疗急性有机磷农药中毒的临床观察与护理体会

Clinical Observation and Nursing Experience of Effect of Long-acting Tuoning in Treatment of AOPP

目的探讨长托宁抢救急性有机磷农药中毒的临床效果与护理体会。方法59名有机磷农药中毒病人被随机分为观察组(30例)和对照组(29例),观察组采用长托品治疗,对照组以阿托品治疗,所有病人均给予护理干预。结果观察组在药物化时间、给药次数、住院时间、CHE恢复时间等方面均优于对照组(P<0.05),心率加快的副作用明显低于对照组(P<0.05),但其引起精神症状的副作用较严重,二组比较差异有统计学意义(P<0.05)。结论长托宁抢救急性有机磷农药中毒效果明显,但药物副作用大,在应用长托宁治疗急性有机磷农药中毒时应注意剂量控制,加强防护,注意安全,防止意外发生。

Objective To explore the clinical therapeutic effect of long acting tuoning and nursing experience in treatment of acute organophosphorus pesticides poisoning （AOPP）. Methods Fifty nine cases with organophosphorus pesticides poisoning were randomly divided into observation group （n = 30） and control group （n = 29）. The observation group were treated with long acting Tuoning, and the control group were treated with atropine. All the patients were given nursing intervention. Results The drug duration, the times of administration, hospitalization time, GHE recovery time in observation group were better than those of the control group （P〈 0.05）, while heart rate in observation group was significantly less than that of the control group （P〈 0.05）. Long- acting tuoning caused more serious side effects. The difference between the two groups was significant （P〈 0.05）. Conclusions The clinical therapeutic effect of long- acting tuoning in the rescue of AOPP is obvious, but with serious side effects. It is necessary to pay attention to dose control, strengthen protection and safety, and prevent accidents.