摘要
髓过氧化物酶是一种主要由中性粒细胞分泌的白细胞酶,在心血管疾病的发生发展中,包括发病初期、发展及动脉粥样硬化急性复合病变期,MPO及其介导的炎症途径促进了动脉粥样硬化的形成,因此MPO可以作为心肌损伤、治疗和预后的标志物。
Myeloperoxidace (Mpo) is a leukocyte derived enzyme that catalyzes the formation of a number of reactive oxidant species. Mpo catalyzed reaction has been attributed to potentially proatherogenic biological activities throughout the evolution of cardiovascular disease, including during initiation, propagation and acute complication phases of the atherosclerotic process. As a result, Mpo and its downstream inflammatory pathways represent targets for myocardial injury, therapeutic and prognosis.
出处
《实用预防医学》
CAS
2009年第2期623-625,共3页
Practical Preventive Medicine