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低浓度聚维酮碘用于眼部手术消毒的效果观察 被引量:13

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摘要 目的:探讨低浓度聚维酮碘在眼科手术消毒中的应用。方法:新西兰大白兔20只,分别用生理盐水、0.025%聚维酮碘洗眼液、0.05%聚维酮碘洗眼液、氯化汞洗眼液冲洗兔眼,通过观察眼刺激性及荧光染色裂隙灯照影检查观察角膜上皮损伤,再用眼科手术患者做结膜囊内细菌菌落培养。结果:0.025%聚维酮碘洗眼液对眼刺激性较小,结膜囊内滴入后24h可引起点状角膜上皮损伤,48h后恢复正常,对结膜囊内细菌的杀灭效果良好,损伤程度及杀菌效果均与氯化汞洗眼液类似;而0.05%聚维酮碘洗眼液可引起明显的眼部刺激性,对角膜上皮损伤也比较严重。结论:0.025%的聚维酮碘洗眼液在眼科手术消毒中的应用值得推广。
出处 《中国医院药学杂志》 CAS CSCD 北大核心 2009年第7期599-600,共2页 Chinese Journal of Hospital Pharmacy
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