我院1989～2007年抗菌药不良反应监测报告

Analysis of Antibiotics Usage and Adverse Reactions Caused by Antibiotics in our Hospital From 1989 to 2007

目的:分析医院抗茵药使用及发生不良反应情况。方法:综合医院全部ADR监测资料中抗菌药发生不良反应情况和近5年抗菌药使用情况进行总结分析。结果:共上报ADR报表1 653份,其中抗菌药发生不良反应739例,占ADR上报数的44.71%。近5年抗菌药使用人数占收治病人总数的79.70%,抗菌药费用占总药费的28.73%,抗菌药不良反应上报数193份,上报率仅为0.21%。结论:我院抗菌药使用率高,但抗菌药药费呈下降趋势。近5年抗菌药ADR上报率低。

Objective： To investigate the usage of antibiotics and adverse reactions caused by antibiotics in the hospital. Method： All the cases with adverse reactions caused by antibiotics recorded in ADR monitoring documents were synthesized and the usage of antibiotics in recent five years was summarized and analyzed. Result： 739 patients had adverse reactions after using antibiotics, which took up 44.71% of all the ADR recordings. In recent five years, 79.70% of the patients used antibiotics. The cost of antibiotics in our hospital took up 28.73% of the total medicine cost. Only 193 patients were reported to have ADR, and the rate of reporting was only 0.21%. Conclusion： The rate of the antibiotics usage was quite high, but the cost of antibiotics was decreased year by year. The reporting rate of ADR caused by antibiotics was very low.