摘要
The stability of Copper, Zinc superoxide dismutase increases remarkably when thelysines on the surface of the enzyme are modified. The fmite difference solution to the Poisson-Boltzman equation (FDPB) method is usedf to calculate the electrostatic interaction between so-lution and enzyme. The resnlts show that the reaction field energy of SOD is reduced by about,1270kJ·mol-1 after modification.
The stability of Copper, Zinc superoxide dismutase increases remarkably when thelysines on the surface of the enzyme are modified. The fmite difference solution to the Poisson-Boltzman equation (FDPB) method is usedf to calculate the electrostatic interaction between so-lution and enzyme. The resnlts show that the reaction field energy of SOD is reduced by about,1270kJ·mol-1 after modification.
出处
《物理化学学报》
SCIE
CAS
CSCD
北大核心
1998年第4期289-292,共4页
Acta Physico-Chimica Sinica
基金
天津市高等教育局重点学科资助
关键词
稳定性
超氧化物歧化酶
化学修饰
溶剂化
Enzyme stability, Finite difference, Superoxide dismutase, Chemical modification,Reaction field energy
