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热力对冻干IgG免疫原性和免疫反应性的影响

Effect of Dry Heating on Antigenicity and Immunoreaction of Lyophilized IgG
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摘要 冻干IgG经80℃2小时和100℃30分钟干热处理后,其抗原决定簇未见明显改变,活性抗原量与对照相同,抗-HBs和抗人IgG等抗体活性未受明显影响。 It was shown by our test results that the antigenic determinant of lyophilized IgG,when treated with 80℃ dry heating for 2 hr or 100℃ for 30 min,did not change,the amount of active antigen in IgG was the same as those of untreated IgG and the antibody activity of anti-HBs and anti-HIgG were not influenced. But if the dose of heat treatment increased to 80℃ for 72 hr or 100℃ for 2 hr, the antigen and antibody activity of IgG were influenced obviously.
出处 《微生物学免疫学进展》 1998年第1期58-63,共6页 Progress In Microbiology and Immunology
关键词 免疫球蛋白G 免疫学活性 热力 抗原抗体反应 Immunoglobulin G IgG immunological activity Heating Reaction betveen antigen and antibody
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