核素心肌显像评价麝香保心丸治疗劳累型心绞痛的疗效

Assessment of Effect of Shexiang Baoxin Pill for Labour Angina Pectoris Patients with Computerized Tomography Myocardial Imaging

目的 :为评价麝香保心丸治疗劳累型心绞痛的疗效。方法 :对 66例住院的劳累型心绞痛患者进行常规治疗与常规治疗加用麝香保心丸治疗的对比观察 ,并采用99mTC 甲氧异丁异腈 (MIBI)心肌单光子发射计算机断层 (SPECT)灌注显像 ,定量评价缺血心肌面积变化。结果 :两组临床总有效率分别为 87 8% ,5 6 0 % ,P <0 0 5。心电图总有效率分别为 70 7% ,5 2 0 % ,P >0 0 5 ,无统计学意义。治疗后核素显像缺血心肌面积分别为 1 8 2± 8 2 %、2 3 8±9 8% ,P <0 0 5 ,再发性心绞痛和心脏事件亦少于对照组。结论 :麝香保心丸治疗劳累型心绞痛有显著疗效。

Objective: To assess the effect of Shexiang Baoxin Pill (SXBXP) for labour angina pectoris. Methods: Effect of 66 patients treated with conventional treatment or conventional treatment plus SXBXP were observed and compared with 99m TC MIBI single photon emission computerized tomography (SPECT) target cardiograph to estimate ischemia myocardial area. Results: The total effective rate was much higher in patients treated with SXBXP than that in patients treated with conventional treatment only (87.8%vs 56%,P<0 05). The effective rate on ECG in the two groups was 70.7% and 52.0% respectively, without significant statistical difference between them(P>0 05). While significant difference was observed in ischemia area of myocardial image between the two groups after treatment, 18.2±8 2%vs 23.8±9 8%,P<0 05. Moreover, the recurrence of angina pectoris and cardiac event were also less in the SXBXP group. Conclusion: the SXBXP was effective for labour angina pectoris.