掌跖角皮症－牙周病综合征

Papillon-Lefevre syndrome

报告1例掌跖角皮症-牙周病综合征。患者男,24岁。2岁时出现掌跖角化,并进行性加重,于14岁时牙周组织出现破坏,甲呈钩形。根据以上特点诊断为掌跖角皮症-牙周病综合征。给予阿维A 30 mg每日1次,复方水杨酸软膏(本院自制)及0.1%维A酸软膏外用,取得明显效果。

Papillon-Lefevre syndrome is a race autosomal recessive inherited disease. This article reports a 24-year-old male presented with hyperkeratosis of palms and soles for 22 years, and the syndromes were getting worse and worse. Peri- odontitis appeared till 14-year-old, the nails were bend. The patient was diagnosed as Papillon-Lefevre syndrome based on special features. The patient responded well after treating with acitretin and some drugs for topical application.