摘要
纤维蛋白原受体拮抗剂能阻止通过各种途径激活的血小板聚集,因而可以有效地抑制血栓的形成。本文综述非肽类纤维蛋白原受体拮抗剂的研究进展,介绍其构效关系。
Fibrinogen receptor antagonists were found to have potent inhibitory effects on the aggregation of platelet activated by a variety of activators, and then,the plateletinduced thrombus formation were blocked.In this paper, the novel nonpeptide fibrinogen receptor antagonists,including their structureactivity relationships were discussed.
出处
《药学进展》
CAS
1998年第1期21-27,共7页
Progress in Pharmaceutical Sciences
关键词
纤维蛋白原
非肽类
拮抗剂
抗血栓形成药
Fibrinogen receptor (GPⅡb/Ⅲa) Nonpeptide fibrinogen receptor antagonists Thrombus