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非肽类纤维蛋白原受体拮抗剂的研究进展 被引量:3

The Progress of the Nonpeptide Fibrinogen Receptor Antagonists
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摘要 纤维蛋白原受体拮抗剂能阻止通过各种途径激活的血小板聚集,因而可以有效地抑制血栓的形成。本文综述非肽类纤维蛋白原受体拮抗剂的研究进展,介绍其构效关系。 Fibrinogen receptor antagonists were found to have potent inhibitory effects on the aggregation of platelet activated by a variety of activators, and then,the plateletinduced thrombus formation were blocked.In this paper, the novel nonpeptide fibrinogen receptor antagonists,including their structureactivity relationships were discussed.
出处 《药学进展》 CAS 1998年第1期21-27,共7页 Progress in Pharmaceutical Sciences
关键词 纤维蛋白原 非肽类 拮抗剂 抗血栓形成药 Fibrinogen receptor (GPⅡb/Ⅲa) Nonpeptide fibrinogen receptor antagonists Thrombus
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