烧伤感染防治对策

Strategies for prevention and cure of burn infection

感染是严重烧伤患者最主要的死亡原因之一。对于严重烧伤患者，抗生素的选择不容忽视，而抗生素的不当使用，加之全身免疫功能低下，会导致患者真菌感染。严重烧伤后脓毒症的治疗是一项复杂的系统工程，除有效的抗休克治疗、早期肠道喂养、清除坏死组织、及早封闭创面外，合理有效的抗生素及抗真菌治疗，免疫调节治疗及防治凝血功能障碍等措施，对清除机体毒素有较好的作用。

Infection is still the major cause of death in severe burn patients, thus the optimization of antibiotic therapy is an important approach to the annihilation of pathogenic bacteria and the decrease of drug-resistance bacteria. It is urgent for burn surgeons to face the selection pressure of antibiotics and the fungous infections following the incorrect use of antibiotics. Regardless of its complexity, the treatment of sepsis associated with post-burn bacterial infections should be systematical. Besides the effective anti-shock therapy, early enteral feeding, excision of necrotic tissues, and effective anti-infection treatment, the immunological regulation and the prevention and cure of coagulation disorders are necessary in the treatment of severely burned patients.