局部亚低温与三七总皂甙联用在脑出血早期中的意义

Clinical Significance of Early Local Mild Hypothermia Combined with PNS on Cerebral Hemorrhage

目的观察局部亚低温与三七总皂甙联用在脑出血早期治疗中的疗效。方法124例急性脑出血患者分为联用组(局部亚低温联用三七总皂甙)、局部亚低温组、三七总皂甙组和对照组,每组31例。观察治疗后神经功能改善情况及临床疗效。结果联用组各时期神经功能缺损SSS评分均显著低于对照组(P<0.05),第14d,第30d显著低于亚低温和三七总皂甙组;联用组的有效率在30d显著高于其它各组(P<0.05)。结论亚低温与三七总皂甙联用能显著促进急性脑出血患者神经功能的恢复,提高疗效。

Objective To observe the effects of local mild hypothermia combined with PNS on cerebral hemorrhage in the early stage. Methods Total 124 acute cerebral hemorrhage patients were divided into combining group （local mild hypothermia combined with PNS）, local mild hypothermia group,PNS group and control group, 31 cases of each group. Observing the improvement of nerve function and clinical efficacy after treatment. Results By SSS neurological deficits score, combining group score were significantly lower than that of the control group （ P 〈 0. 05 ） and were significantly lower than that of mild hypothermia and PNS group at 14,30 days （ P 〈 0.05）. The effective rate in combining group was significantly higher than that of other groups （ P 〈 0.05）. Conclusion Mild hypothermia combined with PNS could significantly promote the nerve function recovery with acute intracerebral hemorrhage patients and enhance the effectiveness of treatment.