摘要
对两个含有超抗原T细胞表位的TSST-1交叠肽之Vβ特异性进行了鉴定。结果显示:两合成肽均具备天然TSST-1分子四种人和小鼠Vβ特异性的两种(人Vβ2和小鼠Vβ15)。表明:两合成肽所含有的超抗原T细胞表位是TSST-1特异性的;同时,两合成肽Vβ特异性的一致性。
Specificity of superantigenic T cell epitopes in 2 over lapping peptides of TSST1 to TCRVβ was examined.The results showed that the two peptides had the identical specificity to Vβ with two of four kinds of TSST1 target TCRVβ s, human Vβ 2 and mouse Vβ 15.Therefore,it is suggested that the T cell epitopes of the peptides are peculiar to TSST1 and located within the common sequence of two over lapping peptides.
出处
《免疫学杂志》
CAS
CSCD
北大核心
1998年第2期75-78,共4页
Immunological Journal
基金
全军"九五"医药卫生科研重点项目基金
国家自然科学基金