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乳腺癌标志物的研究 被引量:1

Research about Markers of Breast Cancer
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摘要 乳腺癌是危害妇女健康主要的恶性肿瘤之一,近年来发病率上升速度最快的恶性肿瘤之一。众所周知,乳腺癌属于全身性疾病,即使是早期乳腺癌,也会发生隐匿性转移。目前乳腺癌标志物已成为研究的一个热点。肿瘤标志物是指与肿瘤发生相关的物质,主要包括两部分:大分子蛋白质肿瘤标志物和基因肿瘤标志物,通过对乳腺癌相关肿瘤标志物的综合研究分析,可以对其发生、恶性程度、预后等作出及时判断,指导治疗,提高患者的生活质量和生存期。 Breast cancer is one of the malignant tumors with highest rising incidence rate in recent years, endangering women's health. It is well known that Breast cancer are systemic diseases, occult metastasis maybe happen even if it is just in its early stage. At present, breast caneer marker has become a research hot. Tumor markers refers to the materials related to tumor genesis and development,which includes maeromolecular protein tumor markers and genetic tumor markers. The general analysis of these markers is helpful to the prompt judgement of its genesis, malignant degree and prognosis, guiding the treatment, and improving the life quality and life span of the patients.
出处 《医学综述》 2009年第8期1156-1159,共4页 Medical Recapitulate
基金 国家自然科学基金(4010107)
关键词 乳腺肿瘤 肿瘤标志物 研究 Breast tumor Tumor marker Research
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  • 1Fiebiger W, Wihschke C. Tumor markers [ J ]. Acta Med Austriaca, 2001,28(2) :33-37.
  • 2Rossi Fanelli F, Cangiano C, Muscaritoli M, et al. Tumor-induced changes in host metabolism : a possible marker of neoplastic disease [J]. Nutrition,1995,11 (5 Suppl) :595-600.
  • 3Kondo H,Nobuoka A. Clinical apphcation of oncogene and antioncogene as a tumor marker[J]. Nippon Rinso,1996,.54(6) :1494-1498.
  • 4Hayes DF, Yamauehi H, Broadwater G, et al. Circulating HER-2/ erbB-2/c-neu(HER-2) extracellular domain as a prognostic factor inpatients with metastatic breast cancer: Cancer and Leukemia GroupB Study 8662 [ J ]. Clin Cancer Res,2001,7 (9) :2703-2711.
  • 5Tanner M, Jarvinen P, Isola J. Amplification of HER-2/neu and topoisomerase Ilalpha in primary and metastatic breast cancer[ J]. Cancer Res,2001,61 (14) :5345-5348.
  • 6Pienkowski T, Olszewski W, Kraszewakas E, et al. Predictive value of HER-2 receptor, p53, bcl-2 and bax proteins, MB-1 antibody,estrogene and progesterone receptor expression in breast cancer patients receiving adjuvant tamoxifen [ J ]. Eur J Cancer, 2002,38 ( Suppl 3 ) : S116-S119.
  • 7Schippinger W,Regitnig P,Bauernhofer T,et al. The course of serum HER-2/neu levels as an independent prognostic for survival in metastatic breast cancer[J]. Oncol Rep,2004,11 (6) :1331-1336.
  • 8Ariga R, Zarif A, Korasick J, et al. Correlation of her-2/neu gene amplification with other prognostic and predictive factors in female breast carcinom a[J]. Breast J,2005,11 (4) :278-280.
  • 9Zahm DM, Greinke C, Noschel H,et al. MSA-a new sensitive tumor marker in breast carcinoma [ J]. Zentralbl Gynakol, 1996, 118(12) :659-664.
  • 10Gion M, Plebani M, Mione R, et al. CA549 in primary breast caneer:Comparison with CA15-3 and MCA[J]. Br J cancer,1994,69 (4) :721-725.

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