重型颅脑损伤后低钠血症的临床分析

Diagnosis and Treatment of Central Hyponatremia after Serious Cerebral injury

目的:分析重型颅脑损伤后低钠血症的临床特点。方法:回顾性分析47例重型颅脑损伤后低钠血症患者临床表现及实验室检查结果。结果:20例符合抗利尿激素分泌异常综合征,其中治愈18例,死亡2例;27例符合脑性盐耗综合征,治愈20例,死亡7例。结论:抗利尿激素分泌异常综合征与脑性盐耗综合征的发病机制与治疗措施不同,对其进行正确诊治能降低颅脑损伤病人的致残率和死亡率。

Objective：To study the clinical features of craniocerebral injury with hyponatremia. Methods： The clinical presentation and laboratory results of 47 patients of craniocerebral injury with central hyponatremia were analysed retrospectively. Results： Syndrome of inappropriate antidiuretic hormone was found in 20 cases,with which 18 patients were cured and 2 patients died. Cerebral saltwasting syndromewere found in 27 cases,with which 20 patientswere cured and 7 patients died. Conclusions： Pathogenesis and management of syndrome of inappropriate antidiuretic hormone complicatedwith craniocerebral injury is different from that- ofcerebral saltwasting syndrome. Early diaglosis and therapy can reduce its morbidity and mortality.