甘油催化氯代法合成二氯丙醇

Synthesis of Dichloropropanols by Catalytic Chlorinated Glycerol

以带羧基侧基的聚芳醚砜醚酮酮(PESEKK-A)为主催化剂,PCl3为助催化剂,考察了两者不同质量比对甘油氯代法合成二氯丙醇的催化效果。结果表明:当PESEKK-A和PCl3用量分别为甘油质量的4.0%和1.5%时,二氯丙醇的收率达89.8%。比较了甲苯带水、二氯乙烷(DCE)连续恒沸带水和二氯乙烷间歇带水3种工艺,实验表明:DCE间歇带水二氯丙醇的收率提高到92.4%,产物中1,3-二氯-2-丙醇的质量分数为96.9%,具有较高的催化氯代选择性。

The synthesis of dichloropronol from chlorinated glycerol using poly （ aryl ether sulfone ether ketone ketone） having pendent carboxyl （PESEKK - A ） as the main catalyst and PCl3 as catalyst promote was performed. The influence of catalytic efficiency of the mass ratio between PESEKK - A and PCl3 was also investigated. The result showed that the yield of diehloropronol was above 89. 8% ,when the amount of PESEKK - A and PCl3 was 4. 0 and 1.5 percent of the mass of glycerol respectively. In this study, toluene dehydration, 1,2-dichloroethane （ DCE ） continuous and intermittent dehydration technique were applied, which indicated that the yield of dichloropronol was over 92. 4% using the intermittent dehydration process. Gas chromatography （ GC ） detected that the mass fraction of 1,3- dichloro-2-pronol was 96.9%. It showed that the synthesized dichloropropanols from catalytic chlorination glycerol was an effective and high selective method by optimized the technical conditions.