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类风湿关节炎患者血清氧化低密度脂蛋白与炎症因子水平的变化 被引量:2

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摘要 类风湿关节炎(rheumatoid arthritis,RA)是临床中常见的慢性自身免疫性疾病,其病理特征表现为进展性关节滑膜损害导致的外周关节炎症[1]。近年来,众多流行病学研究发现,RA患者冠心病的发病率显著高于正常人群[2]。氧化低密度脂蛋白(oxidized low density lipoprotein,ox-LDL)是一种脂质过氧化产物,它可通过多种生物学途径参与动脉粥样硬化(atherosclerosis,AS)的发生及发展,
出处 《中华临床医师杂志(电子版)》 CAS 2012年第23期7888-7889,共2页 Chinese Journal of Clinicians(Electronic Edition)
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  • 1刘青松,蒋红,唐中.丹参对类风湿关节炎患者滑膜细胞肿瘤坏死因子α表达的影响[J].中华临床医师杂志(电子版),2009,3(8):74-76. 被引量:15
  • 2H John,TE Toms,GD Kitas.Rheumatoid arthritis: is it a coronary heart disease equivalent?. Current Opinion in Cardiology . 2011
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  • 6Zhang H,Park Y,Wu J,et al.Role of TNF-alpha in vascular dysfunction. Clinical Science Lond . 2009
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  • 8Ishigaki Y,Oka Y,Katagiri H.Circulating oxidized LDL:a biomarker and a pathogenic factor. Current Opinion in Lipidology . 2009
  • 9Grover HS,Gaba N,Gupta A,et al.Rheumatoid arthritis:a review and dental care considerations. Nepal Med Coll J . 2011
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