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二线抗病毒药物治疗老年艾滋病23例短期疗效分析 被引量:5

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摘要 近年来我国老年艾滋病病毒感染者/艾滋病患者(HIV/AIDS)报道数呈逐年上升趋势[1],在一些地区老年HIV/AIDS的疫情相当严重[2],2010年初二线方案由于其毒副反应比较少而被批准用于老年患者,但在我国该方案用于治疗老年HIV/AIDS的报道罕见,经验非常有限。
出处 《中华临床医师杂志(电子版)》 CAS 2012年第23期7896-7897,共2页 Chinese Journal of Clinicians(Electronic Edition)
基金 广西壮族自治区卫生厅科研课题(Z2011057) 广西壮族自治区南宁市科学研究及技术开发项目基金(南科发:201106039c)
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  • 1王义德,王向阳,李伟,陈建生,陈凡,潘和平,杨林胜.临泉县艾滋病二线抗病毒治疗药物疗效分析[J].安徽医学,2009,30(9):1027-1028. 被引量:2
  • 2梁飞立,何艳英,黄绍标,郑培衡,邓梅花,何燕,苏齐鉴.老年艾滋病抗病毒治疗六年生存情况及其影响因素分析[J].中华临床医师杂志(电子版),2012,6(20):165-166. 被引量:17
  • 3UNAIDS. Together we will end AIDS [ DB/OL [ 2013-3-25 ]. http ://wwwunaidsorg/en./resources/campaigns/togetherwewillen- daids/unaidsreport/.
  • 4Keiser O, Tweya H, Braitstein P, et al. Mortality after failure of antiretroviral therapy in sub-Saharan Africa. Trop Med Int Health, 2010, 15(2) : 251-258.
  • 5Xia Wang, Xing Hui, Yuhua Ruan, et al. Effect of Viral Load and Drug Resistance on Mortality among Chinese HIV-Infected Pa- tients Receiving Antiretroviral Treatment. J Antiviral Antiretrovir, 2012, 4(3) : 60-65.
  • 6Gsponer T, Petersen M, Egger M, et al. The causal effect of switching to second-line ART in programmes without access to routine viral load monitoring. AIDS, 2012, 26(1 ) : 57-65.
  • 7Chetchotisakd P, Anunnatsiri S, Kiertiburanakul S, et al. High rate multiple drug resistances in HI-infected patients faihng non- nucleoside reverse transcriptase inhibitor regimens in Thailand, where subtype A/E is predominant. J Int Assoc Physicians AIDS Care (Chic), 2006, 5(4) : 152-156.
  • 8Marconi VC, Sunpath H, Lu Z, et al. Prevalence of HIV-1 drug resistance after failure of a first highly active antiretroviral therapy regimen in KwaZulu Natal, South Africa. Clin Infect Dis, 2008, 46(10) : 1589-1597.
  • 9Sungkanuparph S, Manosuthi W, Kiertiburanakul S, et al. Op- tions for a second-line antiretroviral regimen for HIV type 1-infec- ted patients whose initial regimen of a fixed-dose combination of stavudine, lamivudine, and nevirapine fails. Clin Infect Dis, 2007, 44(3) : 447-452.
  • 10Hosseinipour MC, van 0osterhout JJ, Weigel R, et al. The publichealth approach to identify antiretroviral therapy failure : high-level nucleoside reverse transcriptase inhibitor resistance among Malaw- ians failing first-line antiretroviral therapy. AIDS, 2009, 23 (9) : 1127-1134.

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