北京50岁及以上男性夜尿患病率调查

The prevalence of nocturia in men aged over 50 years in Beijing

目的调查北京地区50岁及以上男性夜尿患病现状及其与年龄、下尿路症状及膀胱过度活动症(OAB)的相关性。方法采用分层多阶段整群不等比例随机抽样方法选择年龄≥50岁男性作为研究对象。下尿路症状的评估包括国际前列腺症状评分(IPSS)、生活质量(QOL)评分、腹部超声前列腺体积、残余尿量测定和最大尿流率测定。夜尿定义为夜间睡眠过程中≥2次排尿。结果本研究共调查社区中老年男性人群1656人,符合本研究要求的共计1639人。年龄50～89岁,平均(64±10)岁。夜尿的患病率为66.4%(1089/1639)。夜尿的患病率与社区中老年男性的年龄、IPSS评分、QOL评分、残余尿量以及最大尿流率均具有显著相关性(P<0.01)。对年龄以及IPSS评分的分层研究发现,夜尿的患病率随着年龄的增加以及下尿路症状的加重明显升高(P<0.01)。夜尿人群中OAB患病率显著高于非夜尿人群。结论社区中老年男性夜尿的患病率很高,严重影响中老年患者生活质量,是一种常见但未被充分认识的疾病。中老年男性夜尿患病率随年龄增长逐渐增加。

Objective To investigate the prevalence of nocturia in a population of Chinese men aged 50 and over.Methods A cross-sectional study was performed at Beijing Communities in men aged over 50 years.The evaluation of lower urinary tract symptoms(LUTS)including the International Prostate Symptom Score(IPSS),quality of life(QOL)score,prostate volume and post voiding residue(PVR)by abdominal ultrasonography,and maximum flow rate(Qmax).Definition of nocturia was determined as≥2 voids/night.Results 1656 subjects were enrolled and 1639 men met our study criteria.The mean age was(64±10)years.The prevalence of nocturia was 66.4%(1089/1639)and was significantly related to age,IPSS,QOL score,PVR and Qmax(P<0.01).The prevalence of nocturia was closed associated with aging(P<0.01)and degree of LUTS.Conclusions Nocturia is a highly prevalent condition in elder man,which adversely affects quality of life.It is,however,an underreported,understudied,and infrequently recognized problem in adults.The prevalence of nocturia increased with aging of the male population.