160名美沙酮维持治疗病人滥用非阿片类物质行为调查

The Investigation about Non-opioid Arugs Abuse among 160 Outpatients Receiving Methadone Maintenance Treatment

目的调查美沙酮维持治疗者滥用非阿片类物质的行为,为维持治疗策略提供科学依据。方法对参加美沙酮维持治疗的符合条件的海洛因依赖者进行尿检,调查非阿片类物质甲基苯丙胺、亚甲二氧基苯丙胺、氯胺酮以及苯二氮卓物质滥用情况,共完成160例。将尿检结果与患者性别、婚姻状态、文化程度、滥用海洛因方式、年龄、海洛因滥用时间、美沙酮维持治疗剂量、参加美沙酮维持治疗的时间及尿吗啡检测结果等共9个因素进行Lo-gistic回归分析。结果非阿片类物质总的阳性率是14.4%,其阳性率与美沙酮剂量呈正相关(P<0.01)。结论美沙酮维持治疗者存在非阿片类物质滥用的现象,尤其是美沙酮维持量较大者。

Objectives To investigate the non-opioid drugs abused behavior among outpatients who are receiving methadone maintenance treatment,and provide scientific basis for methadone maintenance treatment(MMT).Methods In the MMT clinics,160 heroin addict cases who were accepting MMT were sampled to finish urine non-opioid drugs test,including methamphetamine,methylenedioxy amphetamine,ketamine,buprenorphine.The Logistic regression analysis was used between urine Non-opioid drugs test results and nine factors,such as sex,marital status,education,the way of drug abuse,age,the dose of methadone,MMT time,the result of urine morphine test.Results Positive rate of non-opioid drugs was 14.4%,which was positive interrelated with the dose of methadone.Conclusions Non-opioid drugs abuse was common in MMT,especially in the patients who took more methadone.