左氧氟沙星与依替米星对治疗急性细菌性肠炎的疗效比较

The comparison of levofloxacin and etimicin in curative effect for curing acute bacterial enteritis

目的:从用药时程、用药方式、疗效及不良反应等方面对左氧氟沙星和依替米星治疗急性细菌性肠炎进行比较。方法:将急性细菌性肠炎患者62例随机分为两组,分别用左氧氟沙星和依替米星静脉滴注治疗,并观测疗效和不良反应。结果:治疗第1天、第2天、第3天、第4天、第5天的治愈率,左氧氟沙星为13.3%、30%、53.3%、86.7%、90%,依替米星为6.3%、9.4%、15.6%、53.1%、62.5%;不良反应发生率,左氧氟沙星和依替米星分别为26.7%和3.1%。结论:左氧氟沙星对治疗急性细菌性肠炎的疗效明显高于依替米星,但不良反应较依替米星大。

[Objective]Compared with levofloxacin and etimicin for curing acute bacterial enteritis in medication time course、modality、curative effect and adverse reaction.[Method]We divide 62 patients with acute bacterial enteritis to 2 groups in random,using levofloxacin or etimicin in the way of intervenous drop infusion and surveying the curative effect and adverse reaction. [Result]The cure rates of using levofloxacin to treat the disease after 1st day、2nd day、3rd day、4th day、5th day are 13.3%、30%、53.3%、86.7%、90%,while the cure rates of using etimicin to treat the disease are 6.3%、9.4%、15.6%、53.1%、62.5%.The incidence of adverse reaction of using levofloxacin or etimicin is respectively 26.7%or 3.1%.[Conclusion]Levofloxacin is eminently better than etimicin in curative effect to treat acute bacterial enteritis,while whose adverse reaction is also larger.