下呼吸道感染常见病原菌及耐药性分析

Analysis of the bacterium isolated and the antibiotic resistance of lower resplratory tract infection

目的了解本地区下呼吸道感染的常见病原菌及耐药性。方法药敏试验采用纸片扩散法。结果铜绿假单胞菌、真菌、沙雷氏菌属、大肠埃希菌、克雷伯菌属、不动杆菌属、表皮葡萄球菌、金黄色葡萄球菌和肠球菌是最常见的细菌。甲氧西林耐药金黄色葡萄球菌(MRSA)和甲氧西林耐药凝固酶阴性葡萄球菌(MRCNS)的检出率分别为28.6%和93.1%;产超广谱β-内酰胺酶(ESBLs)的大肠埃希菌和肺炎克雷伯菌的检出率分别为29.3%和22.2%。未发现耐万古霉素的肠球菌。结论细菌耐药性问题是抗感染治疗的主要威胁,合理使用抗生素以降低耐药性和采取有效措施控制其传播是非常重要的。

Objective To investigate the acterium isolated and the antibiotic resistance of lower resplratory tract infection of the patients in home,area.Method Disc diffusion test(K-B) was used to study the antimicrobial resistance.Results P.oeruginosa,Epiphyte,Serratia,E.coli,Klebsiella,Acinetobacter,S.epidermidis,S.aureus,Enterococcus were the most common strains among the isolates.The detectable rates of Methicillin-resistant S.aureus(MRSA) and methicillin-resistant coagulase-negitive staphylococci(MRCNS) were 28.6% and 93.1% respectively.The incidences of E.coli and K.pneumoniae producing extended spectum beta-lactamase isolates were 29.3% and 22.2% respectively.No VRE was found.Conclusion Antimicrobial resistance of clinical isolates threatens the success of infectious disease treatment.It is very important to promote the rational use of antimicrobial agents so that resistance is minimized and take effective containment for the control of the probiem.