SELDI-TOF-MS蛋白质芯片技术在消化系统肿瘤中的研究进展

Advances in digestive tumor using SELDI-TOF-MS protochip technique

随着蛋白质组学研究技术的飞速发展,集样品分离、纯化、检测和数据分析于一体的SELDI蛋白质芯片技术成为蛋白质组学研究的有力工具,在肿瘤的诊断及防治方面发挥了重要作用。文章就其基本原理、特点及在消化系统肿瘤中的应用作一综述。

With the rapid development of proteomics technology,SELDI protein chip technology has become a powerful tool for proteomics with the capacity of gathering sample separation,purification,testing and data analysis together.As its convenience,high-throughput and high-sensitivity,as well as simple and fast analysis,SELDI technology plays an important role in the diagnosis and prevention of tumor.Here we re- view the basic principles,features and recent advances of this technology in digestive tumor.