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胃肠道间质瘤11例临床内窥镜诊断分析

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摘要 目的探讨胃肠道间质瘤(GIST)的临床及内窥镜特征,分析其诊断价值。方法回顾分析11例经手术病理确诊的GIST患者临床病理资料与内窥镜资料(形态、表面情况、大小及诊断),进行比较。结果GIST患者的症状与肿瘤大小、发生部位、肿瘤与肠壁的关系、肿瘤的良恶性有关。良恶性间质瘤内窥镜下大小比较,差异无统计学意义(P>0.05)。内窥镜下表面光滑者85.7%为良性,14.2%为交界性;表面有溃疡或糜烂均为恶性,内窥镜下肿瘤表面情况比较,差异有统计学意义(P<0.01)。结论内窥镜深取与免疫组化CD_(117)及CD_(34)等免疫标记物检测配合可提高GIST的诊断准确率,肿瘤表面的溃疡或糜烂对内窥镜下鉴别良恶性有重要意义。
出处 《肿瘤研究与临床》 CAS 2007年第3期199-200,共2页 Cancer Research and Clinic
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  • 1娄越亮,陈华,张燮良,战忠利.96例胃肠道间质瘤临床诊治分析[J].中华肿瘤杂志,2004,26(7):437-439. 被引量:25
  • 2JuHanLee,XianglanZhang,WoonYongJung,YangSeokChae,Jong-JaePark,InsunKim.DNA ploidy and c-Kitmutation in gastrointestinal stromal tumors[J].World Journal of Gastroenterology,2004,10(23):3475-3479. 被引量:8
  • 3Teng-WeiChen,Hsiao-DungLiu,Rong-YaunShyu,Jyh-CherngYu,Ming-LangShih,Tzu-MingChang,Chung-BaoHsieh.Giant malignant gastrointestinal stromal tumors: Recurrence and effects of treatment with STI-571[J].World Journal of Gastroenterology,2005,11(2):260-263. 被引量:8
  • 4许国铭,金震东,邹多武,邹晓平.超声内镜对上消化道粘膜下肿瘤的诊断[J].中华超声影像学杂志,1995,4(6):241-244. 被引量:40
  • 5Lasota J,Wozniak A,Sarlomo-Rikala M,et al.Mutations in exons 9 and 13 of KIT gene are rare events in gastrointestinal stromal tumors.A study of 200 cases[J].Am J Pathol,2000,157(4):1091-1095.
  • 6Tsuura Y,Hiraki H,Watanabe K,et al.Preferential localization of ckit product in tissue mast cells,basal cells of skin,epithelial cells of breast,small cell lung carcinoma and seminoma/dysgeminoma in human.Immunohistochemical study of formalin-fixed,paraffin-embedded tissues[J].Virchows Arch,1994,424(2):135-141.
  • 7Sakurai S,Fukasawa T,Chong J M,et al.Embryonic form of smooth muscle myosin heavy chain (SMemb/MHC-B) in gastrointestinal stromal tumor and interstitial cells of Cajal[J].Am J Pathol,1999,154(1):23-28.
  • 8Robinson T L,Sircar K,Hewlett B R,et al.Gastrointestinal stromal tumors may originate from a subset of CD34-positive interstitial cells of Cajal[J].Am J Pathol,2000,156(4):1157-1163.
  • 9Torihashi S,Nishi K,Tokutomi Y,et al.Blockade of kit signaling induces transdifferentiation of interstitial cells of cajal to a smooth muscle phenotype[J].Gastroenterology,1999,117(1):140-148.
  • 10Hornick J L,Fletcher C D.Immunohistochemical staining for KIT (CD117) in soft tissue sarcomas is very limited in distribution[J].Am J Clin Pathol,2002,117(2):188-193.

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