甘精胰岛素用于独居的老年2型糖尿病患者的优势

The advantages of insulin glargine in solitary senile patients with type 2 diabetes.

目的探讨甘精胰岛素应用于独居的老年2型糖尿病患者的依从性和疗效。方法 32例独居的老年2型糖尿病患者在原来口服药不变的基础上,加用每天1次甘精胰岛素治疗3个月。结果观察组和对照组的空腹血糖(FBG)分别下降(2.6±1.5)mmoL/L 和(0.3±0.1)mmoL/L(t=1.691,P<0.05);糖基化血红蛋白(HbA_1c)分别下降(1.4±0.6)%和(0.4±0.1)%(t=2.231,P<0.05);低血糖发生人次分别为6次和4次,均非严重低血糖。结论甘精胰岛素可以提高独居的老年2型糖尿病患者的依从性和疗效。

Objective To investigate whether insulin glargine can increase compliance and improve hyperglycemia or not in solitary senile patients with type 2 diabetes.Methods Thirty-two solitary senile patients with type 2 diabetes were given insulin glargine once daily besides the previous oral hypoglycaemic agents.Results FBG decreased(2.6± 1.5)mmol/L and(0.3±0.1)mmol/L in observing and control group respectively(t=1.691,P<0.05).HbA_1c de- creased 1.4%±0.6% and 0.4%±0.1% in the two group respectively(t=2.231,P<0.05).Conclusion Insulin glargine can increase compliance and improve hyperglycemia in solitary senile patients with type 2 diabetes.