肝硬化失代偿期患者心功能改变的研究

Study of the Changes of Cardiac Function in Liver Cirrhosis with ultrasound.

目的观察肝硬化失代偿期患者心功能的改变。方法采用2.5 MHz 探头测量32例肝硬化失代偿期患者(肝硬化组)和35名正常人(对照组)心功能各项指标。测量分别取左室长轴切面,心尖四腔心切面,主动脉短轴切面。各指标以均数±标准差(x^-±s)表示。结果与对照组相比,肝硬化组舒张功能中的二尖瓣舒张早期峰值速度(EV)及 EV 与二尖瓣舒张晚期峰值速度(AV)的比值(EV/AV)明显降低(P<0.01);三尖瓣舒张早期峰值速度(TEV)明显降低(P<0.01);三尖瓣舒张晚期峰值速度(TAV)明显增加(P<0.01);TEV/TAV 明显降低(P<0.01);右心功能中肺动脉瓣加速时间(ACT)明显缩短(P<0.01)。结论肝硬化失代偿期左心舒张功能受累,右心收缩功能和舒张功能均受累。

Objective To observe the changes of cardiac function in liver cirrhosis decompensation stage.Methods This article reports the cardiac function changes of 32 cases liver cirrhosis patients in decompeusation stage as compared with 35 health persons.Some heart parameters are measured.Results In liver cirrhosis decompensation stage the EV of mitral valve and EV/AV in diastole function decreased significantly,the TEV of tricuspid valve decreased(P<0.01),the TAV of tricuspid valve increased(P<0.01),TEV/TAV decreased markedly(P<0.01).In fight cardiac function ACT shortened(P<0.01).Conclusion In the decompensation stage of patients with liver cirrhosis,the left ventricular dias- tole function is affected,the right ventricular systole and diastole functions are affected greatly.