肾小球肾炎病理类型与肾间质纤维化程度对照分析

The relativation study of renal biopsy pathology(RBP)and renal intertitial fibrosis(RIF).

目的观察肾小球肾炎患者肾穿刺病理(RBP)类型与肾间质纤维化(RIF)程度之间的相关性。方法收集经 RBP 确诊的肾小球肾炎患者112例,根据 RIF 程度分为4组,并与 RBP 结果作对照分析。结果根据RIF 程度分为轻度 RIF 组45例,中度 RIF 组22例,重度 RIF 组15例,肾间质无纤维化的30例。肾小球肾炎的病理类型随着肾间质纤维化程度的变化而变化。随着肾间质纤维化程度的加重,IgA 肾病(IgAN)、狼疮性肾炎(LN)、局灶性节段性肾小球硬化(FSGS)的发病率有增加趋势,而系膜增生性肾炎则表现为各种程度 RIF。结论肾间质纤维化程度与肾小球病理损害程度呈正相关。

Objective To investigate the correlation between renal biopsy pathology(RBP) and Renal intertitial fibrosis (RIF).Methods 112 cases of RIF patients were collected in our hospital who had done RBP examination and were di- vided into four groups based on RIF degree.Results 45 cases in light group,22 cases in moderate group,15 cases in se- vere group and 30 cases in control group.With different RIF degree,renal pathology were different.Conclusion IgAN、 LN、FSGS were much more in moderate and severe RIF group compared with those of other groups,MSPGN were seen in any RIF degree groups.