摘要
目的探讨急性心肌梗死患者直接经皮冠状动脉成形术(PTCA)联合脂微球载体前列腺素 E_1(Lipo-PGE_1)治疗后心电图 ST 段改变的临床意义。方法前瞻性研究76例行直接 PTCA 联合 Lipo-PGE1治疗的急性心肌梗死患者术后30 min 心电图 ST 段的改变情况,分析其与治疗效果、心肌损害程度、心功能及预后的关系。结果急性心肌梗死患者直接 PTCA 联合 Lipo-PGE1治疗后心电图 ST 段明显下降者治疗效果好,心肌损害程度减轻,心功能较好。结论直接 PTCA 联合脂微球载体前列腺素 E1治疗急性心肌梗死患者,术后心电图 ST 段改变可作为判定疗效、心肌灌注情况,进而判定预后的指标之一。
Objective The aim of the study is to approach the clinical significance of the change of ST segments after di- rect percutaneous transcoronary angioplasty(PTCA) combined with Lipo-PGE_1 in treating Acute Myocardial Infarction (AMI).Methods The change of the ST segments on EKG of 76 patients with AMI are observed in 30 minutes after un- derwent direct PICA combined with Lipo-PGE_1,and the relations are analyzed that are prospectively to their therapy effect,the degree of injured cardiac muscle,the cardial functions,and the prognosis.Results The patients who treated with the PCTA combined with Lipo-PGE_1 ST segments on EKG 30 minutes after operations reduced significantly,cardiac muscle is injured lowly,their cardial functions are better.Conclusion The change of ST segments after direct percutane- ous transcoronary angioplasty (PTCA) combined with Lipo-PGE_1 in treating acute myocardial infarction is one of the guide line to estimate the perfnsion of cardiac muscle,and to estimate prognosis farther.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2007年第S1期231-234,共4页
Chinese Journal of Practical Internal Medicine