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正电子发射计算机断层扫描肿瘤显像剂应用进展 被引量：1

Radiotracer for cancer imaging of positron emission tomography
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摘要 近几年正电子发射计算机断层扫描(PET)作为分子影像学的代表,正逐渐走向临床,而PET 显像剂也相应发展,其目的就是为临床勾勒出肿瘤解剖形态之外的生物学特征。PET 显像剂种类很多,主要有代谢、乏氧、增生、凋亡、生长因子受体显像剂等。虽然各有优缺点,但相信随着进一步的研究和开发,PET 显像剂将最终会为临床提供可靠、清晰、准确的 PET 图像。 As a representative of molecular imaging,the clinical application of PET modality is in- creasing fast.At the same time,PET tracers are also developed for delineating the biological characters in clinical application,except for the anatomic form.There are many kinds of PET tracers,and the main cate- gories are as the following:metabolic,hypoxia,proliferation,apoptosis and growth factor receptor tracers.Al- though they have their own drawbacks and advantages,it is confident that,with further development and re- search,PET tracers could provide reliable,clear and precise PET images for clinical judgment in the long run.
作者 宋海 司宏伟
机构地区 河北省唐山市人民医院药剂科 中国医学科学院中国协和医科大学肿瘤医院核医学科
出处 《肿瘤研究与临床》 CAS 2007年第9期640-642,共3页 Cancer Research and Clinic
关键词 正电子发射计算机断层扫描 分子影像学 肿瘤 Positron Emission Tomography(PET) Molecular Imaging Tumor
分类号 R730.4 [医药卫生—肿瘤]
  • 相关文献

参考文献27

  • 1巩合义,于金明.PET乏氧显像预测肿瘤疗效研究进展[J].中华核医学杂志,2005,25(1):57-58. 被引量：12
  • 2于金明,邢力刚.功能性影像确定肿瘤放射治疗生物靶区的研究进展[J].中国医学影像学杂志,2004,12(1):53-55. 被引量：12
  • 3Lukas B. Been,Albert J. H. Suurmeijer,David C. P. Cobben,Pieter L. Jager,Harald J. Hoekstra,Philip H. Elsinga.[18F]FLT-PET in oncology: current status and opportunities[J]. European Journal of Nuclear Medicine and Molecular Imaging . 2004 (12)
  • 4Christophe M. M. Lahorte,Jean-Luc Vanderheyden,Neil Steinmetz,Christophe Wiele,Rudi A. Dierckx,Guido Slegers.Apoptosis-detecting radioligands: current state of the art and future perspectives[J]. European Journal of Nuclear Medicine and Molecular Imaging . 2004 (6)
  • 5J. G. Rajendran,D. C. Wilson,E. U. Conrad,L. M. Peterson,J. D. Bruckner,J. S. Rasey,L. K. Chin,P. D. Hofstrand,J. R. Grierson,J. F. Eary,K. A. Krohn.[18F]FMISO and [18F]FDG PET imaging in soft tissue sarcomas: correlation of hypoxia, metabolism and VEGF expression[J]. European Journal of Nuclear Medicine and Molecular Imaging . 2003 (5)
  • 6Wolfgang A. Weber,Hans-Jürgen Wester,Anca L. Grosu,Michael Herz,Brigitte Dzewas,Horst-Jürgen Feldmann,Michael Molls,Gerhard St?cklin,Markus Schwaiger.O-(2-[18F]Fluoroethyl)-l-tyrosine and l-[methyl-11C]methionine uptake in brain tumours: initial results of a comparative study[J]. European Journal of Nuclear Medicine . 2000 (5)
  • 7Wagner HN.Against all odds,nuclear medicine has thrived. British Journal of Radiology . 2002
  • 8Hammond LA,Cavanaugh SX,Thomas CR.An image worth a thousand lives?. Nature Biotechnology . 2004
  • 9Klimas,MT.Positron emission tomography and drug discovery: contributions to the understanding of pharmacokinetics, mechanism of action and disease state characterization. Molecular Imaging and Biology . 2002
  • 10Shim SS,Lee KS,K im BT, et al.Non-small cell lung cancer:prospective comparison of integrated FDG PET/CT and CT alone for preoperative staging [ J]. Radiology . 2005

二级参考文献33

  • 1[1]Ling CC, Humm J, Larson S, et al. Towards multidimensional radiotherapy (MD-CRT): biological imaging and biological conformality. Int J Radiat Oncol Biol Phys, 2000,47(3):551
  • 2[2]Al-Hallaq HA, Zamora M, Fish BL, et al. MRI measurements correctly predict the relative effects of tumor oxygenating agents on hypoxic fraction in rodent BA1112 tumors. Int J Radiat Oncol Biol Phys,2000,47(3):481
  • 3[3]Chapman JD, Schneider RF, Urbain JL, et al. Single-photon emission computed tomography and positron-emission tomography assay for tissue oxygenation. Semin Radiat Oncol,2001,11(1): 47
  • 4[4]Krishna MC, Subramanian S, Kuppusamy P, et al. Magnetic resonance imaging for in vivo assessment for tissue oxygen concentration. Semin Radiat Oncol, 2001,11(1):58
  • 5[5]Alber M, Paulsen F, Eschmann SM, et al. On biologically conformal boost dose optimization. Phys Med Biol ,2003,48(2):31
  • 6[6]Chao KSC; Bosch WR, Mutic S et al. A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys, 2001,49(4):1171
  • 7[7]Cha S, Knopp EA, Johnson G et al. Intracranial mass lesions: dynamic contrast-enhanced susceptibility-weighted echo-planar perfusion MR imaging. Radiology, 2002,223(1):11
  • 8[8]Fuss M, Wenz F, Essig M, et al. Tumor angiogenesis of low-grade astrocytomas measured by dynamic susceptibility contrast-enhanced MRI (DSC-MRI) is predictive of local tumor control after radiation therapy. Int J Radiat Oncol Biol Phys,2001,51(2):478
  • 9[9]Haubner R,Wester HJ, Weber WA, et al. Non-invasive imaging of ανβ 3 integrin expression using a 18F-labeled RGD-containing glycopeptide and positron emission tomography. Cancer Res,2001,61(5):1781
  • 10[10]Anderson H, Price P. Clinical measurement of blood flow in tumours using positron emission tomography: a review. Nucl Med Comm, 2002,23(2):131

共引文献22

同被引文献13

  • 1杨衿记,吴一龙,徐卫平,李东江,黄玉娟,廖日强,张华,黄逸生,周清,徐崇锐.18FDG-PET评价局部晚期和晚期非小细胞肺癌化疗的客观疗效[J].肿瘤研究与临床,2007,19(7). 被引量：7
  • 2李娜,屈辉.骨转移瘤的影像学诊断进展[J].中国医学影像技术,2006,22(1):159-162. 被引量：16
  • 3刘庆伟;刘奇.PET/CT肿瘤学[M]北京:科学出版社,2006313-322.
  • 4Rybak LD,Rosenthal DI. Radiological imaging for the diagnosis of bone metastases[J].Quarterly Journal of Nuclear Medicine,2001,(01):53-64.
  • 5Helms CA,Cann CE,Brunelle FO. Detection of bone-marrow metastases using quantitative computed tomography[J].Radiology,1981,(03):745-750.
  • 6Imamura F,Kuriyama K,Seto T. Detection of bone marrow metastases of small cell lung cancer with magnetic resonance imaging:early diagnosis before destruction of osseous structure and implications for staging[J].Lung Cancer,2000,(03):189-197.doi:10.1016/S0169-5002(99)00105-1.
  • 7Peterson JJ,Kransdorf MJ,O'Connor MI. Diagnosis of occult bone metastases:positron emission tomography[J].Clin Onhop Relat Res,2003,(zk):S120-S128.doi:10.1097/01.blo.0000093051.96273.7c.
  • 8Fogelman I,Cook G,Israel O. Positron emission tomography and bone metastases[J].Seminars in Nuclear Medicine,2005,(02):135-142.doi:10.1053/j.semnuclmed.2004.11.005.
  • 9Grosfield E,Alavi A,Kneeland B. Comparison of radionuclide bone scans and magnetic resonance imaging in detecting spinal metastases[J].Journal of Nuclear Medicine,1993.2191-2198.
  • 10Yin JJ,Pnllock CB,Kelly K. Mechanisms of cancer metastasis to the bone[J].Cell Research,2005,(01):57-62.doi:10.1038/sj.cr.7290266.

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肿瘤研究与临床
2007年 第9期

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