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血管性血友病因子结构功能及在止血、血栓形成中的作用 被引量:1

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摘要 血管性血友病因子(vWF)在止血和血栓形成过程中起重要作用。血浆中vWF为分子量不等的多聚体,vWF多聚体的大小与功能有密切关系,其分子量越大,与血小板结合能力越强,更能促进血小板聚集、血栓形成与微血管病性溶血。与血管性血友病因子裂解酶(vWF-cp)密切相关。因此研究vWF的生物学特性和功能具有重要意义。就vWF的生物合成,结构特点及生物学功能的研究进展作一综述。
作者 王虹 陈世红
出处 《中国社区医师(医学专业)》 2007年第24期6-6,共1页
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