药物洗脱支架直接置入治疗A型和B_1型病变的临床观察

Comparison of CYPHER^( TM) stenting with or without predilation in patients with A and B_1 lesions

目的 评价直接置入药物洗脱支架 (CYPHERTM,codis)在A或B1 型病变的冠心病患者治疗中的安全性、可行性。方法 6 2例接受CYPHERTM 支架直接置入的患者 (直接支架组 )和一般情况匹配的 5 1例球囊扩张后行冠脉支架术的患者 (常规支架组 ) ,比较两组的一般情况 ,冠脉造影及介入治疗即刻和临床随访结果。结果 直接支架组介入操作时间明显短于常规支架组 [(17.2± 8.6 )比 (2 6 .3± 7.1)min ,P <0 .0 1],直接支架组平均扩张压明显高于常规支架组 [(14± 3)比 (12± 1.9)atm ,P<0 .0 1],两组无一例发生介入治疗相关的严重心脏事件。随访期间两组严重心脏不良事件发生率无显著差异。结论 A或B1 型病变的冠心病患者CYPHERTM 支架直接置入术可缩短介入操作时间 ,即刻效果。

Objective To assess the clinical efficacy of direct Stenting (DS) and conventional post-dilation stenting (CS) for A and B1 lesions in Patients with coronary artery disease.Methods Demographic characters, final baloon dilation pressure, instent angiographic results, and long term outcomes were compared between patients receiving DS (n=62) and patients receiving CS(n=51). Results The operation time in DS group was much shorter than that in CS group ( 17.2 ±8.6 min vs 26.3 ±7.1 min, P <0.01). The mean dilating pressure in DS group was significantly higher than that in CS group (14± 3.1 atm vs 12 ±1.9 atm,P <0.01).During the follow up period, there is mot significant difference between DS group on major adverse cordial events(MACE).Conclusions The immediate success rate, complication and midterm follow up results are similar between the direct stenting and conventional stenting groups, while the operation time is shorter in direct stenting group with A and B 1 lesions.