肾上腺髓质素与缺氧缺血性脑损伤
摘要
肾上腺髓质素是一种新发现的生物活性肽,在体内分布广泛,多种组织都有其mRNA表达,它以自分泌或旁分泌方式参与机体多种生理和病理过程的调节。具有扩张血管、降低血压和排钠利尿等作用。在中枢神经系统内作为细胞保护因子,对脑缺氧缺血性损伤起保护作用。
出处
《国际儿科学杂志》
2004年第S1期1-3,共3页
International Journal of Pediatrics
参考文献15
-
1K. Watanabe,M. Takayasu,A. Noda,M. Hara,T. Takagi,Y. Suzuki,J. Yoshia.Adrenomedullin Reduces Ischemic Brain Injury after Transient Middle Cerebral Artery Occlusion in Rats[J]. Acta Neurochirurgica . 2001 (11)
-
2Kitamuro T,Takahashi K,Nakayama M,et al.Induction of adrenomedullin during hypoxia cultured human glioblastoma cells. Journal of Neurochemistry . 2000
-
3Dogan A,Suzuki Y,Koketsu N,et al.Intravenous infusion of adrenomedullin and increase in regional cerebral blood flow and prevention of ischemic brain injury after middle cerebral artery occlusion in rats. Journal of Cerebral Blood Flow and Metabolism . 1997
-
4Watanabe K,Takayasu M.Noda A,et al.Adrenomedullin reduces ischemic brain injury after transient cerebral artery occlusion in rats. Acta Neurochirurgica . 2001
-
5Serrano J,Alonso D,Encinas JM,et al.Adrenomedullin expression is up-regulated by ischemia repefusion in the cerebral cortex of the adult rat. Neuroscience . 2002
-
6Wang X,Yue TL,Barone FC,et al.Discovery of adrenomedullin in rat ischemic cortex and evidence for its role in exacerbating focal brain ischemic damage. Proceedings of the National Academy of Sciences of the United States of America . 1995
-
7Wijdicks EF,Heublein DM,Burnett JC.Increase and uncoupling of adrenomedullin from the natriuretic peptide system in aneurysmal subarachnoid hemorrhage. Journal of Neurosurgery . 2001
-
8Hofbauer KH,Jensen BL,Kunz A,et al.Tissue hypoxygenation activates the adrenomedullin system in vivo. American Journal of Physiology Regulatory . 2000
-
9Hutchinson HG.Trinldade PT,Cunanan DB,et al.Mechanisms of natriuretic-peptide-induced growth inhibition of vasculate smooth muscle cells. Cardiovascular Research . 1997
-
10Kuwasako K,Kida O,Kitamura K,et al.Plasma adrenomedullin in cerebrovascular disease:a possible indicator of endothelial injury. International Journal of Angiology . 1997
-
1杨希秀,李玉华,李鲁生,迟流萤,赵鑫.缺血性脑血管病患者血浆ET、CGRP的含量变化及临床意义[J].放射免疫学杂志,2003,16(5):268-270. 被引量：8
-
2宋玉强,韩仲岩.肾上腺髓质素与脑血管病[J].国外医学（脑血管疾病分册）,2001,9(6):339-342.
-
3陈宁,毛健.促红细胞生成素与缺氧缺血性脑损伤[J].国外医学（儿科学分册）,2002,29(6):312-314. 被引量：7
-
4杨希秀,李玉华,等.缺血性脑血管病患者血浆ET、CGRP含量变化及临床意义[J].中国检验医学与临床,2001,2(4):166-167.
-
5张殿增.肿瘤坏死因子与脑卒中发生机制[J].世界核心医学期刊文摘（眼科学分册）,2003(3):668-671. 被引量：1
-
6郭本标,周名雄.肾上腺髓质素治疗HIE的实验研究进展[J].解剖与临床,2006,11(6):431-432.
-
7刘华,苏志强.溶血磷脂酸与缺血性脑血管病的关系及其临床应用价值[J].哈尔滨医科大学学报,2007,41(6):634-635. 被引量：7
-
8江胜贤.CRH与精神疾病[J].国外医学（精神病学分册）,1991,18(3):145-147.
-
9Meng W,Zhao W,Zhao T,Liu C,Chen Y,Liu H,Sun Y,练桂丽,叶鹏.高血压组织修复中血管紧张素1-7的自分泌和旁分泌功能[J].中华高血压杂志,2015,23(1):98-98.
-
10杨云华,廖维宏.神经系统中的心肌营养素-1及其受体[J].中国临床神经科学,2006,14(2):218-220. 被引量：1
