期刊文献+

癌基因MUC4研究进展 被引量:3

原文传递
导出
摘要 MUC4(mucin4,4型黏蛋白)是新发现的位于3q29的候选癌基因,研究表明,MUC4具有抗粘附、抗免疫识别及促进肿瘤增殖等功能,在肿瘤发生、发展过程中起着重要作用。现就近几年来的研究进展做一简要综述。
作者 陈健 王鲁平
出处 《国际肿瘤学杂志》 CAS 2004年第S1期24-27,共4页 Journal of International Oncology
关键词 MUC4 ERBB2 癌基因
  • 相关文献

参考文献29

  • 1陈健,王鲁平,郭瑞峰,田茹,韩亚玲,徐昕,蔡岩,王明荣.食管癌中癌基因MUC4的变化及临床病理意义[J].诊断病理学杂志,2004,11(2):108-110. 被引量:2
  • 2Llinares K,Escande F,Aubert S,et al.Diagnostic value of MU-C4 immunostaining in distinguishing epithelial mesothelioma and lung adenocarcinoma. Modern Pathology . 2004
  • 3Moniaux N,Escande F,Batra SK,et al.Alternative splicing generates a family of putative secreted and membrane-associated MUC4 mucins. European Journal of Biochemistry . 2000
  • 4Gum JR Jr,Ho JJ,Pratt WS,et al.MUC3 human intestinal m-ucin.Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region. Journal of Biological Chemistry . 1997
  • 5Lopez-Ferrer A,Alameda F,Barranco C,et al.MUC4 expression is increased in dysplastic cervical disorders. Human Pathology . 2001
  • 6Komatsu M,Yee L,Carraway KL.Overexpression of Sialomucin Complex, a Rat Homologue of MUC4, Inhibits Tumor Killing by Lymphokine-activated Killer Cells. Cancer Research . 1999
  • 7McNeer RR,Carraway CA,Fregien NL,et al.Characterization of the expression and steroid hormone control of sialomucin complex in the rat uterus: implications for uterine receptivity. Journal of Cellular Physiology . 1998
  • 8Hollingsworth MA,Strawhecker JM,Caffrey TC,et al.Expression of MUC1, MUC2, MUC3 and MUC4 mucin mRNAs in human pancreatic and intestinal tumor cell lines. International Journal of Cancer . 1994
  • 9Shepherd TG,Kockeritz L,Szrajber MR,et al.The pea3 subfamily ets genes are required for HER2/Neu-mediated mammary oncogenesis. Current Biology . 2001
  • 10Komatsu M,Jepson S,Arang MoE,et al.Muc4/sialomucin complex, an intramembrane modulator of ErbB2/HER2/Neu, potentiates primary tumor growth and suppresses apoptosis in a xenotransplanted tumor. Oncegene . 2001

二级参考文献10

  • 1Komatsu M,Jepson S,Arango ME,et al.MUC4/sialomucin complex,an intramembrane modulator of erb B2/HER2/Neu,potentiates primary tumor growth and suppresses apoptosis in a xenotransplanted tumor[J].Oncogene,2001,20(4):461-470.
  • 2Scott Jepson,Masanobu Komatsu,Bushra Haq,et al.MUC4/sialomucin complex,the intramembrane erb B2 ligand,induces specific phosphorylation of erb B2 and enhances expression of p27kip,but does not activate mitogen-actiated kinase or protein kinase B/Akt pathw
  • 3Swarts MJ,Batra SK,Varshney GC,et al. MUC4 expression increases progressively in pancreatic intraepithelia neoplasia[J].Am J Clin Pathcl,2002,117(5):791-796.
  • 4Wei F,Ni J,Wu SS,et al,Cytogenetic studies of esophageal squamous cell carcinomas in the northern chinese population by comparative genomic hybridization[J],2002,138(1):38-43.
  • 5Moniaux N,Escande F,Surinder K,et al.Alemative splicing generates a family of putative secreted and membrane-associated MUC4 mucins[J].Eur J Biochem,2000,267(14):4536-4544.
  • 6Seregni E,Botti C,Lombardo C,et al.Pattern of mucin gene expression in normal and neoplastic lung tissues[J].Anticancer Res,1996,16(4B):2209-2213.
  • 7Moniaux,N,Nollet,S,Porchet,N,et al.Complete sequence of the human mucin MUC4:a putative cell membrane-associated mucin[J].Biochem J,1999,338(2):325-33.
  • 8Komatsu M,Carraway CA,Fregien NL,et al.Reversible disruption of cell-matrix and cell-cell interactions by overexpression of sialomucin complex[J]. J Biol Chem,1997,272(52):33245-3354.
  • 9Komatsu M,Yee L,Carraway KL.Overexpression of sialomucin complex,a rat homologue of MUC4,inhibits tumor killing by lymphokine-activated killer cells[J]. Cancer Res,1999,59(9):2229-2236.
  • 10Komatsu M,Tatum L,Altman NH,et al.Potentiation of metastasis by cell surface sialomucin complex (rat MUC4), a multifunctional anti-adhesive glycoprotein[J].Int J Cancer,2000,87(4):480-486.

共引文献1

同被引文献18

引证文献3

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部