滕州市志贺菌菌型、耐药谱及R质粒检测研究

Study of the Types of Shigella, Drug Resistancl and R- plamid

本文报道了1986～1998年度滕州市志贺菌型、耐菌谱、耐药性R质粒转移检测情况。从6862例腹泻病人中检出志贺菌812株,阳性率为11.83％,分属于A、B、C、D4个群28个血清型,其中以B群为主,481株占59.24％,C群次之156株占19.21％,A群103株占12.68％,D群72株占8.87％。812株志贺菌80％以上菌株呈敏感和中度敏感,其耐药率均在21.67～95.19％。检测200株志贺菌R质粒接合转移率为52.00％,以B、C群转移率高于A、D群。检测表明,福氏志贺菌仍是我市流行的主要菌群,而细菌耐药性绝大多数为R质粒介导。

Objective To survey types of shigella. drug resistance extent and translation of resistant R -plamid. Methods 812 strains of shigella were detected among 6862 diarrhea patients, Results The total rate was 11.83% . It was divided into groug A, B, C, D, and 28 serum types. Group B was found to be the prevalent group of shigella, constituted 59.24% (481/812), and group C was the minor one, constituted 19.2% (156/812), the tate of group A and D were 12.68% (103/812) , 8.87% (72/812) . More than 80% strains of shiglla were sensitive highly or medially among 812 strains. The drug resistance rate was 21.67% -95.19%. The R - plamid conjunction and translation rate was 52% among 200 atrains of shigella. The translation rate of group 13 and C were highor that of group A and D. Conclusions The surveillance inditated that shigella, Flexeri (group B) is still the prevalent epidemic group of shigella in Tengzhou City, and most resistance of bacteria were introduced by R- plamid.