乙型肝炎表面抗原无症状携带者血清检测结果分析

The analysis of the result of blood serum examining of 1201 HBsAg ASC in diet and public place

[目的]进一步了解HBsAg无症状携带者(ASC)的感染特点,探讨HBsAg滴度与HBeAg、抗-HBe和抗-HBc检出的相关性,为制订ASC的管理措施和消除乙肝传染源提供依据。[方法]1201份HBsAg阳性血清来源于2001年1～12月到我站预防医学门诊进行健康体检的饮食及公共场所从业人员中筛选出的ASC。HBsAg、HBeAg、抗-HBe、抗-HBc,检测利用ELASA法。[结果]HBeAg、抗-HBe、抗-HBc阳性率分别为39.13％、37.46％、67.44％,HBsAg滴度与HBeAg、抗-HBe、抗-HBc关系密切,HBeAg以高滴度为主,抗-HBe则多分布在低滴度者中,而HBsAg滴度的高低与抗-HBc检出关系不大;30岁以下青年人中HBeAg检出明显高于30岁以上中壮年,男女之间无显著性差异。[结论]HBsAg滴度高低与HBV传染性强弱密切相关。

Objective: To know about the character of HBsAg ASC further, and review the correlation between HBsAg and HBeAg, anti - HBe and anti - HBc. To provide the evidence for making the management of ASC and getting rid of its' infec-tors. Methods: We got 1201 positive blood serum from the people who working in diet and public place, who underwent the health examination in our station from January to December in 2000. Then we examined the HBsAg, HBeAg, anti - HBe and anti- HBc by ELASA. Results: The positive rate of HBeAg, anti - HBe and anti - HBc are 39.13%, 37.46% and 67.44% respectively. There are close relationship between HBsAg and HBeAg, anti-HBe and anti-HBc. HBeAg is mainly high degree, anti - HBe in reverse. There are little correlation between HBsAg' s degree and anti - HBc. The positive rates of HBeAg of young (under 30) are significantly higher than the others (over 30). There are not significantly difference between male and female. Conclusion: There are close correlation between HBsAg degree and the ability of infection of HBV.