摘要
The S100 family is a class of calcium regulated proteins with EF hand. They are widely distributed and are implicated in diverse intracellular and extracellular physiological processes. A study of the S100 family using computational biology methods such as multiple sequence alignment, structural alignment and the construction of an evolutionary tree will promote understanding of S100 protein structures and their function, and could provide suggestions for crystallization.
The S100 family is a class of calcium regulated proteins with EF hand. They are widely distributed and are implicated in diverse intracellular and extracellular physiological processes. A study of the S100 family using computational biology methods such as multiple sequence alignment, structural alignment and the construction of an evolutionary tree will promote understanding of S100 protein structures and their function, and could provide suggestions for crystallization.
基金
the National Natural Science Foundationof China(No.39870 174and39970 15 5 )
Project"86 3"(10 3130 30 6 )
Project " 973" (G199990 75 6 0 2 G19990 1190 2and19980 5 110 5 )
