Effects of Cerium Nitrate on Expression of CaM Ⅰ and PMCA Ca^( 2+ ) -ATPase mRNA in Rat Liver

Effects of Cerium Nitrate on Expression of CaM Ⅰ and PMCA Ca^( 2+ ) -ATPase mRNA in Rat Liver

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摘要 The effect of cerium nitrate on expression of CaM Ⅰ and PMCA1b in rat liver was studied by means of reverse transcription-polymerase chain reaction (RT-PCR). The result shows that neither a high dose (50 mg·kg -1 ) nor a low dose (1 mg·kg -1 ) of cerium nitrate induces any alterations of expression of CaM Ⅰ and PMCA 1b mRNA after recurrent intraperitoneal injection of cerium nitrate, which suggests that effect of cerium nitrate on CaM and Ca 2+ -ATPase might be at posttranscription level. The effect of cerium nitrate on expression of CaM Ⅰ and PMCA1b in rat liver was studied by means of reverse transcription-polymerase chain reaction (RT-PCR). The result shows that neither a high dose (50 mg·kg -1 ) nor a low dose (1 mg·kg -1 ) of cerium nitrate induces any alterations of expression of CaM Ⅰ and PMCA 1b mRNA after recurrent intraperitoneal injection of cerium nitrate, which suggests that effect of cerium nitrate on CaM and Ca 2+ -ATPase might be at posttranscription level.

作者杨维东王艇刘洁生雷衡毅杨燕生

出处《Journal of Rare Earths》 SCIE EI CAS CSCD 2001年第3期219-222,共4页 稀土学报（英文版）

基金 theNationalNaturalScienceFoundationofChina ( 2 96710 34 )andFoundationofNaturalScienceofGuangdongProvince ( 980 32 9)

关键词 rare earths cerium nitrate reverse transcription-polymerase chain reaction CaM Ca 2+ -ATPase rare earths cerium nitrate reverse transcription-polymerase chain reaction CaM, Ca 2+ -ATPase

分类号 Q593.2 [生物学—生物化学]

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Effects of Cerium Nitrate on Expression of CaM Ⅰ and PMCA Ca^( 2+ ) -ATPase mRNA in Rat Liver

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