辅酶Q_(10)与胺碘酮合用治疗难治性室性心律失常疗效分析

Analysis of Therapeutic Effectiveness of Combined Application of Coenzyme Q_(10) and Amiodaronum in Curing Difficult Ventricular Arrhythmia

目的 :分析辅酶Q1 0 与胺碘酮合用治疗难治性室性心律失常的疗效。方法 :5 8例室性心律失常的患者随机分为两组。治疗组 ,男性 38例 ,女性 7例。对照组 ,男性 2 1例 ,女性 8例。治疗组口服辅酶Q1 0 10mg ,3次 d ,胺碘酮 0 .2 ,3次 d ,7天后胺碘酮减量 ,以 0 .2g d维持量治疗。对照组口服慢心律 0 .2 ,3次 d。结果 :治疗效果两组有明显差异 ,治疗组显效率 86 .9% ,有效率 13.1% ,总有效率 10 0 %。对照组显效率 6 2 % ,有效率 13% ,总有效率 75 % ,P <0 .0 5。结论 :辅酶Q1 0 加胺碘酮治疗难治性室性心律失常疗效显著。

Objective: To study the combined application of coenzyme Q 10 and amiodaronum in curing difficult ventricular arrhythmia.Method:58 cases of patients were randomly divided into two groups. The treatment group included 7 females and 22 males. The control group included 21males and 8 females. The treatment group was given 10 mg of Coenzyme Q 10 and 0.2 of Amiodaronum Tid. Seven days later,Amiodaronum was reduced in usage.With a maintenance dose of 0.2. Mexiletrum was used in the control group. The difference was significant in the effect of the treatment.Results: The apparent effective rate and average effective rate and total effective rate were 86.9%,13.1%,100% respectively in the creatment group.The apparent effective rate and average effective rate and total effective rate were 62%,13%,75%respectively in the control group. The curing effect is obvious, P <0.05.Conclusion: Coenzymum Q 10 and Amiodaronum are effective in treating difficult ventricular arrhythmia.